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The proteasome function reporter GFPu accumulates in young brains of the APPswe/PS1dE9 Alzheimer’s disease mouse model

Alzheimer’s disease (AD), the most common cause of dementia, is neuropathologically characterized by accumulation of insoluble fibrous inclusions in the brain in the form of intracellular neurofibrillary tangles and extracellular senile plaques. Perturbation of the ubiquitin-proteasome system (UPS)...

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Bibliografski detalji
Glavni autori: Liu, Yanying, Hettinger, Casey L., Zhang, Dong, Rezvani, Khosrow, Wang, Xuejun, Wang, Hongmin
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954921/
https://ncbi.nlm.nih.gov/pubmed/24363091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10571-013-0022-9
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