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The proteasome function reporter GFPu accumulates in young brains of the APPswe/PS1dE9 Alzheimer’s disease mouse model

Alzheimer’s disease (AD), the most common cause of dementia, is neuropathologically characterized by accumulation of insoluble fibrous inclusions in the brain in the form of intracellular neurofibrillary tangles and extracellular senile plaques. Perturbation of the ubiquitin-proteasome system (UPS)...

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Bibliografiska uppgifter
Huvudupphovsmän: Liu, Yanying, Hettinger, Casey L., Zhang, Dong, Rezvani, Khosrow, Wang, Xuejun, Wang, Hongmin
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954921/
https://ncbi.nlm.nih.gov/pubmed/24363091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10571-013-0022-9
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