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Mathematical Modeling of Interleukin-27 Induction of Anti-Tumor T Cells Response

Interleukin-12 is a pro-inflammatory cytokine which promotes Th1 and cytotoxic T lymphocyte activities, such as Interferon-[Image: see text] secretion. For this reason Interleukin-12 could be a powerful therapeutic agent for cancer treatment. However, Interleukin-12 is also excessively toxic. Interl...

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Detalles Bibliográficos
Main Authors: Liao, Kang-Ling, Bai, Xue-Feng, Friedman, Avner
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954918/
https://ncbi.nlm.nih.gov/pubmed/24633175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091844
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