Loss of P2Y(2) Nucleotide Receptors Enhances Early Pathology in the TgCRND8 Mouse Model of Alzheimer’s Disease

Neuroinflammation is a prominent feature in Alzheimer’s disease (AD) and activation of the brain’s innate immune system, particularly microglia, has been postulated to both retard and accelerate AD progression. Recent studies indicate that the G protein-coupled P2Y(2) nucleotide receptor (P2Y(2)R) i...

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Bibliografische gegevens
Hoofdauteurs: Ajit, Deepa, Woods, Lucas T., Camden, Jean M., Thebeau, Christina N., El-Sayed, Farid G., Glen, W. Greeson, Erb, Laurie, Petris, Michael J., Miller, Douglas C., Sun, Grace Y., Weisman, Gary A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954904/
https://ncbi.nlm.nih.gov/pubmed/24193664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-013-8577-5
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