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Loss of P2Y(2) Nucleotide Receptors Enhances Early Pathology in the TgCRND8 Mouse Model of Alzheimer’s Disease

Neuroinflammation is a prominent feature in Alzheimer’s disease (AD) and activation of the brain’s innate immune system, particularly microglia, has been postulated to both retard and accelerate AD progression. Recent studies indicate that the G protein-coupled P2Y(2) nucleotide receptor (P2Y(2)R) i...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ajit, Deepa, Woods, Lucas T., Camden, Jean M., Thebeau, Christina N., El-Sayed, Farid G., Glen, W. Greeson, Erb, Laurie, Petris, Michael J., Miller, Douglas C., Sun, Grace Y., Weisman, Gary A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954904/
https://ncbi.nlm.nih.gov/pubmed/24193664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-013-8577-5
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