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Loss of P2Y(2) Nucleotide Receptors Enhances Early Pathology in the TgCRND8 Mouse Model of Alzheimer’s Disease

Neuroinflammation is a prominent feature in Alzheimer’s disease (AD) and activation of the brain’s innate immune system, particularly microglia, has been postulated to both retard and accelerate AD progression. Recent studies indicate that the G protein-coupled P2Y(2) nucleotide receptor (P2Y(2)R) i...

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Detalhes bibliográficos
Main Authors: Ajit, Deepa, Woods, Lucas T., Camden, Jean M., Thebeau, Christina N., El-Sayed, Farid G., Glen, W. Greeson, Erb, Laurie, Petris, Michael J., Miller, Douglas C., Sun, Grace Y., Weisman, Gary A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954904/
https://ncbi.nlm.nih.gov/pubmed/24193664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-013-8577-5
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