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Deregulation of Mitochondria-Shaping Proteins Opa-1 and Drp-1 in Manganese-Induced Apoptosis

Mitochondria are dynamic organelles that undergo fusion and fission processes. These events are regulated by mitochondria-shaping proteins. Changes in the expression and/or localization of these proteins lead to a mitochondrial dynamics impairment and may promote apoptosis. Increasing evidence corre...

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Detalhes bibliográficos
Main Authors: Alaimo, Agustina, Gorojod, Roxana M., Beauquis, Juan, Muñoz, Manuel J., Saravia, Flavia, Kotler, Mónica L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954806/
https://ncbi.nlm.nih.gov/pubmed/24632637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091848
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