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Tumor Targeting of a cell penetrating peptide by fusing with a pH-sensitive histidine-glutamate co-oligopeptide

Cell penetrating peptides (CPPs) have been well established as potential carriers for intracellular delivery of protein/peptide therapeutics. However, their lack of selectivity impedes their application in vivo. In order to increase their specificity, a highly pH-sensitive histidine-glutamate (HE) c...

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Bibliographic Details
Main Authors: Fei, Likun, Yap, Li-Peng, Conti, Peter S., Shen, Wei-Chiang, Zaro, Jennica L.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954778/
https://ncbi.nlm.nih.gov/pubmed/24508076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2014.01.047
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