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High-resolution intravital imaging reveals that blood derived macrophages but not resident microglia facilitate secondary axonal dieback in traumatic spinal cord injury

After traumatic spinal cord injury, functional deficits increase as axons die back from the center of the lesion and the glial scar forms. Axonal die back occurs in two phases: an initial axon intrinsic stage that occurs over the first several hours and a secondary phase which takes place over the f...

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Detalhes bibliográficos
Main Authors: Evans, Teresa A., Barkauskas, Deborah S., Myers, Jay, Hare, Elisabeth G., You, Jingquang, Ransohoff, Richard M., Huang, Alex Y., Silver, Jerry
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954731/
https://ncbi.nlm.nih.gov/pubmed/24468477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2014.01.013
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