Recombinant Human Activated Protein C in the Treatment of Acute Respiratory Distress Syndrome: A Randomized Clinical Trial

RATIONALE: Pulmonary coagulopathy may play a pathogenetic role in acute respiratory distress syndrome (ARDS), by contributing to alveolocapillary inflammation and increased permeability. Recombinant human activated protein C (rh-APC) may inhibit this process and thereby improve patient outcome. METH...

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Autori principali: Cornet, Alexander D., Groeneveld, A. B. Johan, Hofstra, Jorrit J., Vlaar, Alexander P., Tuinman, Pieter R., van Lingen, Arthur, Levi, Marcel, Girbes, Armand R. J., Schultz, Marcus J., Beishuizen, Albertus
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954619/
https://ncbi.nlm.nih.gov/pubmed/24632673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090983
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