CCR2 Gene Deletion and Pharmacologic Blockade Ameliorate a Severe Murine Experimental Autoimmune Neuritis Model of Guillain-Barré Syndrome

The molecular determinants and signaling pathways responsible for hematogenous leukocyte trafficking during peripheral neuroinflammation are incompletely elucidated. Chemokine ligand/receptor pair CCL2/CCR2 has been pathogenically implicated in the acute inflammatory demyelinating polyradiculoneurop...

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Autori principali: Yuan, Furong, Yosef, Nejla, Lakshmana Reddy, Chetan, Huang, Ailing, Chiang, Sharon C., Tithi, Hafiza Rahman, Ubogu, Eroboghene E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954548/
https://ncbi.nlm.nih.gov/pubmed/24632828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090463
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