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Adenovirus replication and transcription sites are spatially separated in the nucleus of infected cells.

We have visualized the intranuclear topography of adenovirus replication and transcription in infected HeLa cells. The results show that viral DNA replication occurs in multiple foci that are highly organized in the nucleoplasm. Pulse-chase experiments indicate that newly synthesized viral double-st...

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Detalhes bibliográficos
Main Authors: Pombo, A, Ferreira, J, Bridge, E, Carmo-Fonseca, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC395454/
https://ncbi.nlm.nih.gov/pubmed/7957073
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