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A nucleosome precludes binding of the transcription factor Pho4 in vivo to a critical target site in the PHO5 promoter.

Activation of the Saccharomyces cerevisiae PHO5 gene by phosphate starvation is accompanied by the disappearance of two pairs of positioned nucleosomes that flank a short hypersensitive region in the promoter. The transcription factor Pho4 is the key regulator of this transition. By in vitro footpri...

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Bibliografiske detaljer
Udgivet i:EMBO J
Principais autores: Venter, U, Svaren, J, Schmitz, J, Schmid, A, Hörz, W
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1994
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395424/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7957054/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06811.x
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