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Haplotype structure and positive selection at TLR1

Toll-like receptor 1, when dimerized with Toll-like receptor 2, is a cell surface receptor that, upon recognition of bacterial lipoproteins, activates the innate immune system. Variants in TLR1 associate with the risk of a variety of medical conditions and diseases, including sepsis, leprosy, tuberc...

詳細記述

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書誌詳細
主要な著者: Heffelfinger, Christopher, Pakstis, Andrew J, Speed, William C, Clark, Allison P, Haigh, Eva, Fang, Rixun, Furtado, Mahohar R, Kidd, Kenneth K, Snyder, Michael P
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3953919/
https://ncbi.nlm.nih.gov/pubmed/24002163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2013.194
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