Immortalization of multipotent growth-factor dependent hemopoietic progenitors from mice transgenic for GATA-1 driven SV40 tsA58 gene.

The transcription factor GATA-1 is required for the normal development of erythroid cells. GATA-1 is also expressed in other hemopoietic cells, suggesting that it might be initially activated in a multipotent progenitor. To immortalize GATA-1-expressing progenitors, we generated mice transgenic for...

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Main Authors: Cairns, L A, Crotta, S, Minuzzo, M, Moroni, E, Granucci, F, Nicolis, S, Schiró, R, Pozzi, L, Giglioni, B, Ricciardi-Castagnoli, P
Format: Artigo
Language:Inglês
Published: 1994
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC395390/
https://ncbi.nlm.nih.gov/pubmed/7925299
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