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Developmental regulation of alpha beta T cell antigen receptor expression results from differential stability of nascent TCR alpha proteins within the endoplasmic reticulum of immature and mature T cells.

The alpha beta T cell antigen receptor (TCR) that is expressed on most T lymphocytes is a multisubunit transmembrane complex composed of at least six different proteins (alpha, beta, gamma, delta, epsilon and zeta) that are assembled in the endoplasmic reticulum (ER) and then transported to the plas...

Celý popis

Uloženo v:
Vydáno v:EMBO J
Hlavní autoři: Kearse, K P, Roberts, J L, Munitz, T I, Wiest, D L, Nakayama, T, Singer, A
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 1994
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395383/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7925292/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06772.x
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