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Functional expression of a rat homologue of the voltage gated either á go-go potassium channel reveals differences in selectivity and activation kinetics between the Drosophila channel and its mammalian counterpart.

We have cloned a mammalian (rat) homologue of Drosophila ether á go-go (eag) cDNA, which encodes a distinct type of voltage activated potassium (K) channel. The derived Drosophila and rat eag polypeptides share > 670 amino acids, with a sequence identity of 61%, exhibiting a high degree of simila...

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Detalhes bibliográficos
Main Authors: Ludwig, J, Terlau, H, Wunder, F, Brüggemann, A, Pardo, L A, Marquardt, A, Stühmer, W, Pongs, O
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC395377/
https://ncbi.nlm.nih.gov/pubmed/7925287
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