Identification of a novel mitochondrial uncoupler that does not depolarize the plasma membrane()

Dysregulation of oxidative phosphorylation is associated with increased mitochondrial reactive oxygen species production and some of the most prevalent human diseases including obesity, cancer, diabetes, neurodegeneration, and heart disease. Chemical 'mitochondrial uncouplers' are lipophil...

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Bibliografische gegevens
Hoofdauteurs: Kenwood, Brandon M., Weaver, Janelle L., Bajwa, Amandeep, Poon, Ivan K., Byrne, Frances L., Murrow, Beverley A., Calderone, Joseph A., Huang, Liping, Divakaruni, Ajit S., Tomsig, Jose L., Okabe, Kohki, Lo, Ryan H., Cameron Coleman, G., Columbus, Linda, Yan, Zhen, Saucerman, Jeffrey J., Smith, Jeffrey S., Holmes, Jeffrey W., Lynch, Kevin R., Ravichandran, Kodi S., Uchiyama, Seiichi, Santos, Webster L., Rogers, George W., Okusa, Mark D., Bayliss, Douglas A., Hoehn, Kyle L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2013
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3953706/
https://ncbi.nlm.nih.gov/pubmed/24634817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2013.11.005
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