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Transcription of the lymphocyte-specific terminal deoxynucleotidyltransferase gene requires a specific core promoter structure.

The terminal deoxynucleotidyltransferase (TdT) gene encodes a template-independent DNA polymerase that is expressed exclusively in immature lymphocytes. The TdT promoter lacks a TATA box, but an initiator element (Inr) overlaps the transcription start site. The Inr directs basal transcription and al...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Garraway, I P, Semple, K, Smale, S T
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1996
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39537/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8633066/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.9.4336
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