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Identification of pro-thymocytes in murine fetal blood: T lineage commitment can precede thymus colonization.

Phenotype and commitment of thymus-colonizing precursors are unknown. Here we report the identification of T lineage-committed precursors (designated prothymocytes) in murine fetal blood at day 15.5 of development. Fetal blood pro-thymocytes are Thy-1+c-kit(low)CD3- in contrast to fetal blood-derive...

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Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Rodewald, H R, Kretzschmar, K, Takeda, S, Hohl, C, Dessing, M
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 1994
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395350/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7523109/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06743.x
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