Autophagy-Related IRGM Polymorphism Is Associated with Mortality of Patients with Severe Sepsis

OBJECTIVE: Autophagy is the regulated catabolic process for recycling damaged or unnecessary organelles, which plays crucial roles in cell survival during nutrient deficiency, and innate immune defense against pathogenic microorganisms. Autophagy has been also reported to be involved in various cond...

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Main Authors: Kimura, Tomonori, Watanabe, Eizo, Sakamoto, Teruo, Takasu, Osamu, Ikeda, Toshiaki, Ikeda, Kazumi, Kotani, Joji, Kitamura, Nobuya, Sadahiro, Tomohito, Tateishi, Yoshihisa, Shinozaki, Koichiro, Oda, Shigeto
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3953488/
https://ncbi.nlm.nih.gov/pubmed/24626347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091522
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