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Modulation of Phagosomal pH by Candida albicans Promotes Hyphal Morphogenesis and Requires Stp2p, a Regulator of Amino Acid Transport

Candida albicans, the most important fungal pathogen of humans, has a unique interaction with macrophages in which phagocytosis induces a switch from the yeast to hyphal form, allowing it to escape by rupturing the immune cell. While a variety of factors induce this switch in vitro, including neutra...

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Detalhes bibliográficos
Main Authors: Vylkova, Slavena, Lorenz, Michael C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3953444/
https://ncbi.nlm.nih.gov/pubmed/24626429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003995
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