Didemnin binds to the protein palmitoyl thioesterase responsible for infantile neuronal ceroid lipofuscinosis.

Eitemau Tebyg

• The crystal structure of palmitoyl protein thioesterase 1 and the molecular basis of infantile neuronal ceroid lipofuscinosis
  gan: Bellizzi, John J., et al.
  Cyhoeddwyd: (2000)
• Human palmitoyl protein thioesterase: evidence for lysosomal targeting of the enzyme and disturbed cellular routing in infantile neuronal ceroid lipofuscinosis.
  gan: Hellsten, E, et al.
  Cyhoeddwyd: (1996)
• Lipid thioesters derived from acylated proteins accumulate in infantile neuronal ceroid lipofuscinosis: correction of the defect in lymphoblasts by recombinant palmitoyl-protein thioesterase.
  gan: Lu, J Y, et al.
  Cyhoeddwyd: (1996)
• Human recombinant palmitoyl protein thioesterase-1 (PPT1) for preclinical evaluation of enzyme replacement therapy for infantile neuronal ceroid lipofuscinosis
  gan: Lu, Jui-Yun, et al.
  Cyhoeddwyd: (2009)
• Subdural Effusion and Infantile Neuronal Ceroid Lipofuscinosis
  gan: J Gordon Millichap
  Cyhoeddwyd: (2010-02-01)