Antifibrotic Effects of Noscapine through Activation of Prostaglandin E(2) Receptors and Protein Kinase A

Myofibroblast differentiation is a key process in the pathogenesis of fibrotic disease. We have shown previously that differentiation of myofibroblasts is regulated by microtubule polymerization state. In this work, we examined the potential antifibrotic effects of the antitussive drug, noscapine, r...

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Detalhes bibliográficos
Main Authors: Kach, Jacob, Sandbo, Nathan, La, Jennifer, Denner, Darcy, Reed, Eleanor B., Akimova, Olga, Koltsova, Svetlana, Orlov, Sergei N., Dulin, Nickolai O.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3953264/
https://ncbi.nlm.nih.gov/pubmed/24492608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.546812
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