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Smooth muscle-specific switching of alpha-tropomyosin mutually exclusive exon selection by specific inhibition of the strong default exon.

Exons 2 and 3 of alpha-tropomyosin are spliced in a strict mutually exclusive manner. Exon 3 is a default choice, being selected in almost all cell types where the gene is expressed. The default selection arises from a competition between the two exons, in which the stronger branch point/pyrimidine...

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Библиографические подробности
Опубликовано в::EMBO J
Главные авторы: Gooding, C, Roberts, G C, Moreau, G, Nadal-Ginard, B, Smith, C W
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 1994
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395299/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8070413/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06697.x
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