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Elucidating the ensemble of functionally-relevant transitions in protein systems with a robotics-inspired method

BACKGROUND: Many proteins tune their biological function by transitioning between different functional states, effectively acting as dynamic molecular machines. Detailed structural characterization of transition trajectories is central to understanding the relationship between protein dynamics and f...

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Bibliografiske detaljer
Main Authors: Molloy, Kevin, Shehu, Amarda
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3952944/
https://ncbi.nlm.nih.gov/pubmed/24565158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-13-S1-S8
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