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Elucidating the ensemble of functionally-relevant transitions in protein systems with a robotics-inspired method

BACKGROUND: Many proteins tune their biological function by transitioning between different functional states, effectively acting as dynamic molecular machines. Detailed structural characterization of transition trajectories is central to understanding the relationship between protein dynamics and f...

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Detalhes bibliográficos
Principais autores: Molloy, Kevin, Shehu, Amarda
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3952944/
https://ncbi.nlm.nih.gov/pubmed/24565158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6807-13-S1-S8
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