TLR9 and MyD88 are crucial for the maturation and activation of dendritic cells by paromomycin–miltefosine combination therapy in visceral leishmaniasis

BACKGROUND AND PURPOSE: The combination of paromomycin–miltefosine is a successful anti-leishmanial therapy in visceral leishmaniasis (VL). This encouraged us to study its effect on Toll-like receptor (TLR)-mediated immunomodulation of dendritic cells (DC), as DC maturation and activation is crucial...

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Autori principali: Das, Sushmita, Rani, Mukta, Rabidas, Vidyanand, Pandey, Krishna, Sahoo, Ganesh Chandra, Das, Pradeep
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2014
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Research Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3952803/
https://ncbi.nlm.nih.gov/pubmed/24670148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12530
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