Interleukin-7 is produced by afferent lymphatic vessels and supports lymphatic drainage

The cytokine interleukin (IL)-7 exerts essential roles in lymph node (LN) organogenesis and lymphocyte development and homeostasis. Recent studies have identified lymphatic endothelial cells (LECs) as a major source of IL-7 in LNs. Here, we report that LECs not only produce IL-7, but also express th...

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Autori principali: Iolyeva, Maria, Aebischer, David, Proulx, Steven T., Willrodt, Ann-Helen, Ecoiffier, Tatiana, Häner, Simone, Bouchaud, Grégory, Krieg, Carsten, Onder, Lucas, Ludewig, Burkhard, Santambrogio, Laura, Boyman, Onur, Chen, Lu, Finke, Daniela, Halin, Cornelia
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2013
Soggetti:
Vascular Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3952712/
https://ncbi.nlm.nih.gov/pubmed/23963040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-01-478073
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