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A Novel Lipid Droplet-Associated Serine Hydrolase Regulates Macrophage Cholesterol Mobilization

OBJECTIVE: Lipid-laden macrophages or foam cells are characterized by massive cytosolic lipid droplet (LD) deposition containing mostly cholesterol ester (CE) derived from the lipoproteins cleared from the arterial wall. Cholesterol efflux from foam cells is considered to be atheroprotective. Since...

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Detalhes bibliográficos
Main Authors: Goo, Young-Hwa, Son, Se-Hee, Kreienberg, Paul B., Paul, Antoni
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3952429/
https://ncbi.nlm.nih.gov/pubmed/24357060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.113.302448
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