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Polymer-Enhanced Delivery Increases Adenoviral Gene Expression in an Orthotopic Model of Bladder Cancer

Gene therapy has garnered significant attention as a therapeutic approach for bladder cancer but efficient delivery and gene expression remain major hurdles. The goal of this study was to determine if cationic polymers can enhance adenoviral gene expression in cells that are difficult to transduce i...

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Detalhes bibliográficos
Main Authors: Gosnell, Helen, Kasman, Laura M., Potta, Thrimoorthy, Vu, Lucas, Garrett-Mayer, Elizabeth, Rege, Kaushal, Voelkel-Johnson, Christina
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3952388/
https://ncbi.nlm.nih.gov/pubmed/24370892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2013.12.012
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