Genotype-independent decrease in plasma dopamine beta-hydroxylase activity in Alzheimer’s disease

The noradrenergic system is involved in the etiology and progression of Alzheimer’s disease (AD) but its role is still unclear. Dopamine beta-hydroxylase (DBH) as a catecholamine-synthesizing enzyme plays a central role in noradrenaline (NA) synthesis and turnover. Plasma DBH (pDBH) activity shows w...

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Main Authors: Mustapic, Maja, Presecki, Paola, Pivac, Nela, Mimica, Ninoslav, Hof, Patrick R., Simic, Goran, Folnegovic-Smalc, Vera, Muck-Seler, Dorotea
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3952071/
https://ncbi.nlm.nih.gov/pubmed/23416088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pnpbp.2013.02.002
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