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Doublecortin recognizes the 13-protofilament microtubule cooperatively and tracks microtubule ends

Neurons, like all cells, face the problem that tubulin forms microtubules with too many or too few protofilaments (pfs). Cells overcome this heterogeneity with the γ-tubulin ring complex, which provides a nucleation template for 13-pf microtubules. Doublecortin (DCX), a protein that stabilizes micro...

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Bibliografiska uppgifter
Huvudupphovsmän: Bechstedt, Susanne, Brouhard, Gary J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951992/
https://ncbi.nlm.nih.gov/pubmed/22727374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.05.006
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