A cell-specific enhancer far upstream of the mouse tyrosinase gene confers high level and copy number-related expression in transgenic mice.

The tyrosinase gene encodes the key enzyme of melanin production and is tightly regulated during development. A yeast artificial chromosome covering the mouse tyrosinase gene has been shown to rescue completely the albino phenotype of recipient mouse strains, conferring copy number-dependent, positi...

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Argitaratua izan da:	EMBO J
Egile Nagusiak:	Ganss, R, Montoliu, L, Monaghan, A P, Schütz, G
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Nature Publishing Group 1994
Gaiak:	Research Article
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395199/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8039502/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06607.x
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