Comparative analysis of different biofactories for the production of a major diabetes autoantigen

The 65-kDa isoform of human glutamic acid decarboxylase (hGAD65) is a major diabetes autoantigen that can be used for the diagnosis and (more recently) the treatment of autoimmune diabetes. We previously reported that a catalytically-inactive version (hGAD65mut) accumulated to tenfold higher levels...

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Main Authors: Avesani, Linda, Merlin, Matilde, Gecchele, Elisa, Capaldi, Stefano, Brozzetti, Annalisa, Falorni, Alberto, Pezzotti, Mario
Format: Artigo
Jezik:Inglês
Izdano: Springer International Publishing 2013
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Original Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951962/
https://ncbi.nlm.nih.gov/pubmed/24142387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11248-013-9749-9
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