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Bidirectional regulation of intravenous general anesthetic actions by α3-containing γ-aminobutyric acid(A) receptors

BACKGROUND: γ-aminobutyric acid(A) (GABA(A)) receptors mediate the actions of several intravenous general anesthetics. However, the contribution of α3-containing GABA(A) receptors to the action of these drugs is unknown. METHODS: We compared anesthetic endpoints (hypnosis, immobility, hypothermia) i...

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Bibliografiske detaljer
Main Authors: Straub, Carolin J., Lau, Hew Mun, Parlato, Rosanna, Schuetz, Guenther, Fritschy, Jean-Marc, Rudolph, Uwe
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951843/
https://ncbi.nlm.nih.gov/pubmed/23303487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/ALN.0b013e3182800d76
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