Structural Characterization of the Glycoprotein GP2 Core Domain from the CAS Virus, a Novel Arenavirus-Like Species

Fusion of the viral and host cell membranes is a necessary first step for infection by enveloped viruses and is mediated by the envelope glycoprotein. The transmembrane subunits from the structurally defined “class I” glycoproteins adopt an α-helical “trimer-of-hairpins” conformation during the fusi...

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Main Authors: Koellhoffer, Jayne F., Dai, Zhou, Malashkevich, Vladimir N., Stenglein, Mark D., Liu, Yanyun, Toro, Rafael, S. Harrison, Joseph, Chandran, Kartik, DeRisi, Joseph L., Almo, Steven C., Lai, Jonathan R.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier Ltd. 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951589/
https://ncbi.nlm.nih.gov/pubmed/24333483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.12.009
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