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Targeting SUR1/Abcc8-Type Neuroendocrine K(ATP) Channels in Pancreatic Islet Cells

ATP-sensitive K(+) (K(ATP)) channels play a regulatory role in hormone-secreting pancreatic islet α-, β- and δ-cells. Targeted channel deletion would assist analysis and dissection of the intraislet regulatory network. Toward this end Abcc8/Sur1 flox mice were generated and tested by crossing with g...

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Detalhes bibliográficos
Main Authors: Nakamura, Yumiko, Bryan, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951447/
https://ncbi.nlm.nih.gov/pubmed/24621811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091525
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