Chimeric Proton-Pumping Rhodopsins Containing the Cytoplasmic Loop of Bovine Rhodopsin

G-protein-coupled receptors (GPCRs) transmit stimuli to intracellular signaling systems. Rhodopsin (Rh), which is a prototypical GPCR, possesses an 11-cis retinal. Photoisomerization of 11-cis to all-trans leads to structural changes in the protein of cytoplasmic loops, activating G-protein. Microbi...

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Bibliographic Details
Main Authors: Sasaki, Kengo, Yamashita, Takahiro, Yoshida, Kazuho, Inoue, Keiichi, Shichida, Yoshinori, Kandori, Hideki
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951393/
https://ncbi.nlm.nih.gov/pubmed/24621599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091323
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