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Genetic and molecular analyses of mutations involved in Drosophila raf signal transduction.

We have identified dominant mutations that suppress the lethality associated with an R217-->L mutation in the GTP.Ras binding region (CR1) of the Drosophila raf (D-raf) serine/threonine kinase. Four intragenic and seven extragenic suppressors were recovered. Each of the four intragenic mutations...

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Detalhes bibliográficos
Main Authors: Lu, X, Melnick, M B, Hsu, J C, Perrimon, N
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC395133/
https://ncbi.nlm.nih.gov/pubmed/8013459
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