Novel Point Mutations and A8027G Polymorphism in Mitochondrial-DNA-Encoded Cytochrome c Oxidase II Gene in Mexican Patients with Probable Alzheimer Disease

Mitochondrial dysfunction has been thought to contribute to Alzheimer disease (AD) pathogenesis through the accumulation of mitochondrial DNA mutations and net production of reactive oxygen species (ROS). Mitochondrial cytochrome c-oxidase plays a key role in the regulation of aerobic production of...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Loera-Castañeda, Verónica, Sandoval-Ramírez, Lucila, Pacheco Moisés, Fermín Paul, Macías-Islas, Miguel Ángel, Alatorre Jiménez, Moisés Alejandro, González-Renovato, Erika Daniela, Cortés-Enríquez, Fernando, Célis de la Rosa, Alfredo, Velázquez-Brizuela, Irma E., Ortiz, Genaro Gabriel
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2014
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3950951/
https://ncbi.nlm.nih.gov/pubmed/24701363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/794530
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi