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The centrosomal kinase NEK2 is a novel splicing factor kinase involved in cell survival
NEK2 is a serine/threonine kinase that promotes centrosome splitting and ensures correct chromosome segregation during the G2/M phase of the cell cycle, through phosphorylation of specific substrates. Aberrant expression and activity of NEK2 in cancer cells lead to dysregulation of the centrosome cy...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2014
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3950702/ https://ncbi.nlm.nih.gov/pubmed/24369428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1307 |
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