Ly-6A is required for T cell receptor expression and protein tyrosine kinase fyn activity.

To characterize the function of the Ly-6A antigen in T cell activation, antisense Ly-6 RNA was expressed in a stably transfected antigen-specific T cell clone. Reduced Ly-6A expression results in inhibition of responses to antigen, anti-TCR (anti-T cell receptor) crosslinking and concanavalin A plus...

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Enregistré dans:
Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Lee, S K, Su, B, Maher, S E, Bothwell, A L
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 1994
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395070/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8187770/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06493.x
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