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Promoter occupancy of the basal class I transcription factor A differs strongly between active and silent VSG expression sites in Trypanosoma brucei

Monoallelic expression within a gene family is found in pathogens exhibiting antigenic variation and in mammalian olfactory neurons. Trypanosoma brucei, a lethal parasite living in the human bloodstream, expresses variant surface glycoprotein (VSG) from 1 of 15 bloodstream expression sites (BESs) by...

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Detalhes bibliográficos
Main Authors: Nguyen, Tu N., Müller, Laura S. M., Park, Sung Hee, Siegel, T. Nicolai, Günzl, Arthur
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3950698/
https://ncbi.nlm.nih.gov/pubmed/24353315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1301
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