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Causal inference of gene regulation with subnetwork assembly from genetical genomics data
Deciphering the causal networks of gene interactions is critical for identifying disease pathways and disease-causing genes. We introduce a method to reconstruct causal networks based on exploring phenotype-specific modules in the human interactome and including the expression quantitative trait loc...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3950678/ https://ncbi.nlm.nih.gov/pubmed/24322297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1277 |
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