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Soybean greatly reduces valproic acid plasma concentrations: A food–drug interaction study
The aim of this study was to investigate the effects of soy on the pharmacokinetics and pharmacodynamics of valproic acid (VPA). In a preclinical study, rats were pretreated with two different amounts of soy extract for five days (150 mg/kg and 500 mg/kg), which resulted in decreases of 57% and 65%...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3950581/ https://ncbi.nlm.nih.gov/pubmed/24618639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04362 |
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