A sequence related to a DNA recognition element is essential for the inhibition by nucleotides of proton transport through the mitochondrial uncoupling protein.

The uncoupling protein (UCP) is uniquely expressed in brown adipose tissue, which is a thermogenic organ of mammals. The UCP uncouples mitochondrial respiration from ATP production by introducing a proton conducting pathway through the mitochondrial inner membrane. The activity of the UCP is regulat...

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Udgivet i:EMBO J
Main Authors: Bouillaud, F, Arechaga, I, Petit, P X, Raimbault, S, Levi-Meyrueis, C, Casteilla, L, Laurent, M, Rial, E, Ricquier, D
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1994
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395041/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8168495/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1994.tb06468.x
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