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Antibiotic-induced shifts in the mouse gut microbiome and metabolome increase susceptibility to Clostridium difficile infection

Antibiotics can have significant and long lasting effects on the gastrointestinal tract microbiota, reducing colonization resistance against pathogens including Clostridium difficile. Here we show that antibiotic treatment induces substantial changes in the gut microbial community and in the metabol...

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Detalhes bibliográficos
Main Authors: Theriot, Casey M., Koenigsknecht, Mark J., Carlson, Paul E., Hatton, Gabrielle E., Nelson, Adam M., Li, Bo, Huffnagle, Gary B., Li, Jun, Young, Vincent B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3950275/
https://ncbi.nlm.nih.gov/pubmed/24445449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4114
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