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Glucocorticoid-Mediated Enhancement of Glutamatergic Transmission May Outweigh Anti-Inflammatory Effects under Conditions of Neuropathic Pain

At the clinical level comorbidity between chronic pain and dysfunctional hypothalamus-pituitary-adrenal (HPA) axis is well established. We aimed to identify causal relationships in a model of neuropathic pain (chronic constriction injury, CCI) by studying the effects of glucocorticoid receptor agoni...

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Autors principals: Le Coz, Glenn-Marie, Anton, Fernand, Hanesch, Ulrike
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3950185/
https://ncbi.nlm.nih.gov/pubmed/24618816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0091393
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