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Viruses and Type 1 diabetes: a dynamic labile equilibrium

Type 1 diabetes (T1D) results from the specific immune-mediated destruction of the insulin-producing β-cells of the pancreas. In genetically susceptible individuals, a still undetermined initiating ‘hit’ triggers a cascade of events that eventually leads to autoreactive CD8 T cells infiltrating the...

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Bibliographic Details
Main Authors: Schneider, Darius A, von Herrath, Matthias G
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949992/
https://ncbi.nlm.nih.gov/pubmed/24634696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/dmt.13.17
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