Identification of the sites in MAP kinase kinase-1 phosphorylated by p74raf-1.

Many growth factors whose receptors are protein tyrosine kinases stimulate the MAP kinase pathway by activating first the GTP-binding protein Ras and then the protein kinase p74raf-1. p74raf-1 phosphorylates and activates MAP kinase kinase (MAPKK). To understand the mechanism of activation of MAPKK,...

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Autors principals: Alessi, D R, Saito, Y, Campbell, D G, Cohen, P, Sithanandam, G, Rapp, U, Ashworth, A, Marshall, C J, Cowley, S
Format: Artigo
Idioma:Inglês
Publicat: 1994
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC394991/
https://ncbi.nlm.nih.gov/pubmed/8157000
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