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A Metabonomic Analysis of Serum from Rats Treated with Ricinine Using Ultra Performance Liquid Chromatography Coupled with Mass Spectrometry

A metabonomic approach based on ultra performance liquid chromatography coupled with mass spectrometry (UPLC/MS) was used to study the hepatotoxicity of ricinine in rats. Potential biomarkers of ricinine toxicity and toxicological mechanism were analyzed by serum metabonomic method. The significant...

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Autors principals: Peng, Jing, Cai, Shuang, Wang, Lin, Zhao, Nan, Zhang, Ting-jian, Chen, Zai-xing, Meng, Fan-hao
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949718/
https://ncbi.nlm.nih.gov/pubmed/24618672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090416
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