MRI-Based Computational Model of Heterogeneous Tracer Transport following Local Infusion into a Mouse Hind Limb Tumor

Systemic drug delivery to solid tumors involving macromolecular therapeutic agents is challenging for many reasons. Amongst them is their chaotic microvasculature which often leads to inadequate and uneven uptake of the drug. Localized drug delivery can circumvent such obstacles and convection-enhan...

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Detaylı Bibliyografya
Asıl Yazarlar: Magdoom, Kulam Najmudeen, Pishko, Gregory L., Rice, Lori, Pampo, Chris, Siemann, Dietmar W., Sarntinoranont, Malisa
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949671/
https://ncbi.nlm.nih.gov/pubmed/24619021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0089594
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