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Penta-O-galloyl-β-D-glucose ameliorates inflammation by inhibiting MyD88/NF-κB and MyD88/MAPK signalling pathways

BACKGROUND AND PURPOSE: The gallnut of Rhus chinensis MILL and its main constituent penta-O-galloyl-β-D-glucose (PGG) inhibited NF-κB activation in LPS-stimulated peritoneal and colonic macrophages. Here we have investigated PGG mechanisms underlying anti-inflammatory effects of PGG in vitro and in...

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Autori principali: Jang, Se-Eun, Hyam, Supriya R, Jeong, Jin-Ju, Han, Myung Joo, Kim, Dong-Hyun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Publishing Ltd 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3949655/
https://ncbi.nlm.nih.gov/pubmed/23941302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12333
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